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Cream
Brand :Megacort 0.1%
Generic Name:Mometasone Furoate
Pharmacological Classification: Corticosteroid (topical)
Effect Mechanism:

•Corticosteroids diffuse across cell membranes and bind with specific cytoplasmic receptors. These complexes
then enter the cell nucleus, bind to DNA (chromatin), and stimulate transcription of mRNA and subsequent protein synthesis of various inhibitory enzymes responsible for the anti inflammatory effects of topical corticosteroids.


Indications :

Mild to moderate atopic dermatitis. 

• Contact dermatitis. 

Inflammation and itching.

Eczema

Sunburn

Psoriasis 

Consumption during pregnancy and lactation:

FDA Pregnancy Category C.

It is not known whether topical corticosteroids are distributed into breast milk.

Tell your doctor if you are pregnant or breast feeding. 

Common side effects :

Systemic side effects:

 Hyperglycemia , Glycosuria and HPA axis suppression, Cushing's syndrome.

local side effects:

Allergic contact dermatitis (burning, itching, redness, stinging and thinning of the skin), acne, pustules, purpura, changes in the skin pigmentation, infection. 

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