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Tablet
Brand :Diclofenac Sodium ER 100
Generic Name:Nonsteroidal anti-inflammatory drug (NSAID).
Effect Mechanism:

NSAIDs inhibit the activity of the enzyme cyclo-oxygenase, resulting in decreased formation of precursors of prostaglandins and thromboxanes from arachidonic acid.


Indications :

Treatment of rheumatic diease: Arthritis rheumatoid, Osteoarthritis, Ankylosing spondylitis.

Checkable items

 Regular visits to physician during prolonged therapy. 

possibility that use of alcohol may increase the risk of ulceration and, with phenylbutazone, depressant effects. . Not taking 2 or more NSAIDs concurrently. 

Importance of immediately reporting to physician symptoms of edema, gastrointestinal bleeding or ulceration, cardiovascular events, unusual weight gain, or skin rash.

.Caution if any sugery is required because of possible enhanced bleeding.

. Caution if confusion, dizziness or lightheadedness, drowsiness, or vision problems occur.

. Possibility of gastrointestinal ulceration and bleeding. . Notifying physician immediately if influenza-like symptoms occur shortly prior to or together with a skin rash; rarely. These symptoms may indicate a serious reaction to the medication.

. Missed dose: Taking as soon as possible if remembered within one or two hours after dose should have been taken; skipping dose if not remembered until later.

. Swallowing whole, not breaking, chewing or crushing before swallowing.

. Safety and efficacy have not been established in children.

Consumption during pregnancy and lactation:

. FAD pregnancy category:B.

.Diclofenac is distributed into breast milk.

Common side effects :

 1-Stopping medication and obtaining emergency treatment if symptoms of any of the following occur: Anaphylaxis, anagioedema, or bronchospasm.

2-Stopping medication and checking with physician immediately if symptoms of the following occur: Spitting up blood, unexplained nosebleeds, chest pain, convulsions, fainting, gastrointestinal ulceration or bleeding and blood dyscrasias.

3- Signs and symptoms of other potential side effect: Diarrhea, constipation, gas or bloating, headache, dizziness, ringing in the ears, unexplained weight gain, excessive tiredness, lack of energy, nausea, loss of appelite, itching, yellowing of the skin or eyes, fiurlike symptoms, fever, blisters, rash, hives, swelling of the eyes, face, tongue, lips, throat, arms, hands, feet, ankled, or lower legs, difficulty breathing or swallowing, hoarseness, pale skin, fast heartbeat, cloudy discolored or bloody urine, back pain, difficult or painful urination. Diclofenac may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

Common side effects of drug interactions:

Combinations containing any of the following medication, depending on the amount present may interact with this medication: ACE inhibitors, Acetaminophen, Alcohol, Corticosteroids, oral glucocorticoid, Corticotropin, Potassium supplements; Anticoagulants, coumarin-or indanedione derivative or Heparin, Thrombolytic agents, such as: Alteplase, Anistreplase, Streptokinase, Urokinase, Warfarin, Antidiabetic agents, oral or Insulin, Antihypertensives or diuretics, especially Triamterene; Aspirin or NSAIDs, two or more concurrently, Cefamandole, Cofeoperazone, Cefotetan, Plicamycin, Valpropic acid; Colchicine, Cyclosporine or Gold compounds, Digitals glycosides, Lithium, Methotrexate, Other photosensitizing medication; Platelet aggregation inhibitors, Probenecid, Potassium-sparing diuretics

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