Products

For Acetaminophen :
-Analgesic: Acetaminophen may act predominantly by inhibiting prostaglandin synthesis in the central nervous
system (CNS).
-Antipyretic: Acetaminophen probably produces antipyresis by acting centrally on the hypothalamic heart-regulating
center to produce peripheral vasodilation resulting in increased blood flow through the skin, sweating and heat loss.
-Caffeine is central nervous system stimulant

Acetaminophen:
-Oral: Rapid and almost complete.
-Distribution:
In breast milk: Peak concentrations of 10 to 15 mcg per mL (66.2 to 99.3 micromoles /L) have been measured 1 to
2 hours following maternal ingestion of a single 650-mg dose. The half life in breast milk is 1.35 to 3.5 hours.
Half- life: 1 to 4 hours.
Time to peak concentration: 0.5 to 2 hours.
Elimination
Renal, as metabolites, primarily conjugates: 3% of a dose may be excreted unchanged.
Caffeine:
Caffeine is absorbed readily after oral administration Maximal plasma concentration are achieved in adults within
one hour and the plasma half-life is about 3 to 7 hours-caffeine is almost completely metabolized in the liver by
oxidation, demethylation and acetylation to various xanthine derivatives, which are excreted in the urine.
Storage
Store below 30 °C.