Medipharm Tretinoin Topical Cream

Tretinoin is a derivative of vitamin A that was recognized as the first topical retinoid by the FDA and this substance caused a great revolution in the pharmaceutical industry. This raw material is used in many skin care and health products, including topical tretinoin gel and acne acne gel. Strong tretinoin is produced worldwide in the forms of creams, products, gels and lotions.

In fact, tretinoin is a retinoid metabolite of vitamin A and reduces the adhesion of follicular epithelial cells by reducing the formation of microcomedones. It also leads to the removal of various types of acne and comedones by stimulating mitotic activity and increasing the production of epithelial cells.

One of the products of Kish Medipharm Pharmaceutical Company is topical tretinoin gel with doses of 0.025% and 0.05% tretinoin, which was created after tretinoin was formulated with clindamycin phosphate, resulting in the product Acnemis. Acnemis topical gel is considered a strong anti-acne agent with its synergy. In general, it can be said that topical tretinoin gel has the following properties:

• Anti-aging
• Collagen production
• Reduces clogged pores
• Increase skin elasticity
• Anti-inflammatory and exfoliating
• Increases the cell growth process

Uses of tretinoin topical gel

With its mechanism of action and properties, tretinoin topical gel is considered one of the best products for reducing acne and is considered one of the first choices of dermatologists. Tretinoin topical gel is a specialist in treating acne and acne (acne vulgaris). Other uses of tretinoin topical gel include the following:

• Keratosis pilaris treatment
• Reducing skin freckles
• Removing skin discoloration
• Improves cracked lips and dryness
• Improvement of acute promyelocytic leukemia
• Reducing fine skin wrinkles
• Tretinoin gel for acne and acne scars
• Treatment and reduction of stretch marks (striae)
• Smaller and unclogs open skin pores
• Reducing damage caused by sunlight and UV rays
• Improves acne scars and wounds by increasing collagen production.
• Treatment and improvement of psoriasis, rosacea, alopecia, melasma and lichen planus
• Increases local blood circulation, resulting in improved skin appearance
• Improving skin disorders caused by underlying problems such as liver disease, thyroid, and diabetes
• Exfoliation and reduction of skin melatonin, followed by the removal of dark spots and hyperpigmentation

Contraindications for using tretinoin topical gel

Although tretinoin gel is considered one of the best types of skin products, it is not suitable for everyone. This drug is available in pharmacies across the country, but you should remember that before using it, your physical condition, concomitant medications, age, gender, and severity of the condition should be fully explained to a specialist. Contraindications to the use of tretinoin topical gel can be due to one of the aforementioned conditions, so you should use this medicinal product according to the opinion of a specialist. In summary, we have listed the contraindications to the use of tretinoin topical gel below:

• Symptoms of severe sunburn
• Children and adolescents under 18 years of age
• People with very sensitive skin
• Concomitant use of other exfoliants
• Allergy to tretinoin
• Eczema and very acute inflammations
• After chemical peeling
• Severe skin dryness
• Pregnancy and breastfeeding
• Having open wounds
• Skin infection
• Intention to become pregnant

Side effects of tretinoin topical gel

Taking 2 or more medications at the same time can cause unwanted problems. These problems can be caused by excessive effects of one or both medications or by aggravating the side effects of the medications. It is necessary to identify the side effects of tretinoin topical gel before using any medication, including this product, so that if you see them, you can follow up immediately and prevent more serious disorders. The most obvious side effects of tretinoin topical gel include the following:

• Swelling and inflammation
• Dryness and flaking
• Burning, itching, and redness of the skin
• Excessive sensitivity to the sun and sunlight
• Skin sensitivity to other health products during treatment with tretinoin topical gel

Drug interactions of tretinoin topical gel

As we have previously stated, one of the side effects of a medication can be due to the simultaneous use of several substances or several types of medications, this is called a drug interaction. Drug interactions of tretinoin topical gel can occur if used simultaneously with the following other products:

• Grapefruit
• Contraceptives
• Other strong exfoliants
• Other topical retinoids
• Supplement with vitamin A content
• Corticosteroid medications
• Alcohol-based cleansers and toners
• Anticoagulants (warfarin)
• Antidepressants (sertraline)
• Topical antibiotics (clindamycin, erythromycin, gentamicin, and tetracycline)
• Products containing (benzoyl peroxide, urea, salicylic acid, BHA, AHA, lactic acid)
• Topical antivirals (interferon alpha cream or gel, eicosanoids, ganciclovir, acyclovir)
• Topical antifungals (clotrimazole, ketoconazole, econazole, miconazole, sertaconazole, ciclopirox)

Tips about Terpinoin topical gel

Given that topical tretinoin gel is a type of vitamin A derivative, excessive use can lead to vitamin A toxicity. It is also better to know some tips about how and when to use tretinoin gel, its storage conditions, and warnings before using it. We have tried to explain the most important things you should know about tretinoin gel:

• This medicinal product should be stored at a temperature below 30°C, away from sunlight, and in a dry place.
• Tretinoin topical gel should be kept out of the reach of children.
• Using this product during pregnancy can pose irreparable risks. Due to the mechanism of action of this drug and its entry into the bloodstream, it may even cause miscarriage. During pregnancy, instead of using topical tretinoin gel, it is better to consult your doctor and find an alternative.
• You should not use this product as a long-term treatment and should only take it as prescribed by your doctor.
• Wash your hands thoroughly and thoroughly before and after using tretinoin topical gel. Rinse the affected area with lukewarm water and pat dry.
• Do not use cosmetics for at least 1 hour after applying tretinoin topical gel. Always try to use non-comedogenic cosmetics.
• The best time to use tretinoin topical gel is in the late hours of the day, before bed, and it should be used once a day.
• The results of using this medicinal product usually appear after a few weeks or even months. Don't worry if you experience some dryness and inflammation on the skin surface, it will disappear after a short period of use.
• It is normal to experience small, superficial pimples at the beginning of a period of using topical tretinoin gel, and after the skin gets used to this substance, these minor side effects will disappear.
• Tretinoin topical gel should never come into contact with mucous membranes, including the mouth, nose, and eyes. If contact occurs, seek emergency medical attention immediately.
• Given that during the treatment of skin problems with topical tretinoin gel, the skin becomes very sensitive to the sun, be sure to use sunscreen, especially on the affected area.
• This product is intended for external, topical use only and should be applied to the skin surface.
• Tretinoin topical gel is available in a 15-gram tube with an instruction sheet inside the box at pharmacies with a doctor's prescription.

Conclusion

Tretinoin topical gel is one of the most famous and well-known skin treatment products. This pharmaceutical product has managed to make its place in the minds of people as an emergency anti-acne treatment by treating skin problems such as acne. It should be noted that another Kish Medipharm product, Acnemis topical gel, is produced from the synergy of tretinoin and clindamycin.

Although there are many benefits to using topical tretinoin gel, it is not suitable for everyone and their current condition should be taken into account. Be sure to carefully read the drug interactions and side effects section of the leaflet that comes with each medication before starting it.

It should be noted that the above-mentioned items are solely intended to raise public awareness and improve the health of the people of our beloved homeland and are in no way a substitute for the advice of your specialist physician.