Description
Sumatriptan Plus Tablet is a product of Kish Medipharm Pharmaceutical Company that contains 85 mg of sumatriptan and 500 mg of naproxen. This pharmaceutical product is produced and supplied in tablet form in packs of 8. Sumatriptan Plus Tablet is prescribed to reduce the severity of cluster and migraine headaches and reduce the frequency of attacks.
Agonist of serotonin receptors of the HT1D-5 and HT1B-5 type, which leads to a secondary inhibitory effect on the release of CGR peptide, which is an inflammatory neuropeptide. Also, the mechanism of action of sumatriptan plus tablets is such that it reduces headache by causing contraction in the blood vessels. In addition, it is likely that it also has anti-irritant effects on the trigeminal nerve.
Naproxen, contained in Sumatriptan Plus tablets, is considered a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain by inhibiting cyclooxygenase enzymes and subsequently reducing the production of prostaglandins and thromboxanes from arachidonic acid.
Indications for use of Sumatriptan Plus tablets (sumatriptan and naproxen)
Sumatriptan Plus tablets, with their strong formulation, have been welcomed by many specialists and are considered a strong pain reliever. Below are some of the uses of Sumatriptan Plus tablets:
- Improving and treating headaches and migraines caused by climate change
- Acute treatment of migraine with or without aura in adults and children 12 years of age and older
- Improving and preventing headaches caused by hormonal changes
- Improved quality of life (in people with migraine headaches)
- Preventing cluster headaches associated with migraines
- Relieving pain behind the eyes caused by migraines
- Reducing side effects of other migraine medications
- Improving pulsating and throbbing headaches
- Preventing chronic and acute migraines
- Reducing inflammation associated with headaches
- Treatment of migraine with nausea
- Reduce the frequency of migraine attacks
- Controlling pressure in the blood vessels of the head
Precautions or contraindications for using Sumatriptan Plus tablets
As mentioned, Sumatriptan Plus tablets are formulated with the active ingredients naproxen and sumatriptan. Although this pharmaceutical product can improve the daily functioning of many people, it should be said that it is not suitable for everyone and should only be prescribed upon the diagnosis of a treating physician.
It is better to inform your specialist doctor about all the medications you are taking, your underlying diseases, and your genetic history for better guidance. The doctor will carefully examine and monitor the patient's condition and recommend the best treatment plan. Below are some of the precautions or contraindications for taking Sumatriptan Plus tablets:
- History of coronary artery disease or coronary artery spasm
- History of cardiovascular problems and surgeries
- History of stroke, transient ischemic attack
- Peripheral vascular disease
- Uncontrolled blood pressure
- Recent use (within 24 hours) of another 5-HT1 agonist (e.g., another triptan) or ergotamine-containing medications
- Concurrent or recent use (past 2 weeks) of a monoamine oxidase-A inhibitor such as phenelzine
- History of asthma, hives, other allergic reactions, rhinitis, or nasal polyps after taking aspirin or other painkillers/NSAIDs
- Severe liver failure
- Pregnancy
- Breastfeeding
- Allergy to naproxen
- Allergy to sumatriptan
Some drug interactions of Sumatriptan Plus Tablets (sumatriptan and naproxen)
As you know, one of the most obvious causes of unwanted problems after taking medications is drug interactions. Drug interactions, in addition to causing complications, can lead to a decrease or increase in the effectiveness of medications. We will now mention some of the drug interactions of Sumatriptan Plus tablets containing sumatriptan and naproxen:
- Alcohol
- ACE inhibitors and ARBs
- Ergotamine-containing compounds and other triptan-containing compounds
- Monoamine oxidase-A inhibitors such as phenelzine
- Medications that affect the blood clotting system such as warfarin, aspirin, selective serotonin reuptake inhibitors such as sertraline
Side effects of Sumatriptan Plus tablets (naproxen and sumatriptan)
Problems that arise after taking medications can be mild, moderate or severe, and if any symptoms worsen, you should immediately go to the emergency room or see a specialist. To avoid unwanted side effects, it is better to inform your doctor of all the necessary things and also read the brochure inside the product box carefully. Side effects of Sumatriptan Plus (naproxen and sumatriptan) tablets can occur as follows:
- Dizziness
- Drowsiness
- Nausea
- Indigestion
- Dry mouth
- Hot flashes
- Muscle cramps
- Numbness of hands and feet
- Chest discomfort and pain, feeling of pain/pressure/stiffness in the neck, throat, jaw
Conclusion
Sumatriptan Plus tablets (sumatriptan and naproxen) are one of the products produced by Kish Medipharm Pharmaceutical Company, which is used to treat and reduce migraine headaches and prevent migraine recurrence.
This medicinal product is a pain reliever prescribed by a doctor and it is best to use it until the end of the recommended course of treatment. If you have been prescribed Sumatriptan Plus tablets, do not recommend them to anyone else as they may not be suitable for them and may cause unwanted side effects.
Remember that Sumatriptan Plus Tablets (sumatriptan and naproxen) are not suitable for treating non-migraine headaches. It is best to drink plenty of fluids and stay hydrated while using this medicinal product.
It should be noted that all of the above is stated for the purpose of social responsibility to inform the community and you should not stop or take Sumatriptan Plus tablets arbitrarily. The attending physician will definitely recommend the best treatment options to the referring person by observing, monitoring, conducting tests and clinical observations.
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