Description
Clotrimazole is an antifungal drug from the arysol class that is commonly used to treat fungal infections. Fungi usually develop between the toes, in the hair, on the skin, and even in the vagina. This drug is produced in the formats of vaginal tablets, vaginal suppositories, lotions, solutions, creams, and clotrimazole ointments. Clotrimazole 1% topical cream is produced by Kish Medipharm Pharmaceutical Company and is easily available and purchased in pharmacies across the country.
The mechanism of action of clotrimazole is to change the permeability of the fungal cell membrane by binding to phospholipids, which leads to intracellular elements. In fact, by inhibiting the biosynthesis of triglycerides and phospholipids, as well as preventing the activity of the peroxidase enzyme, followed by an increase in the toxic concentration of hydrogen peroxide, it prevents the formation of the cell wall and also inhibits the growth and cell division of the fungus. In fact, this drug prevents the reproduction of the fungi that have been created by destroying them and ultimately eliminates this fungal infection.
Uses of topical clotrimazole 1% cream and ointment
As mentioned, Clotrimazole cream from Medipharm prevents the formation of cell walls and inhibits the growth and division of fungi by inhibiting the biosynthesis of ergosterol or other sterols, as well as the activity of peroxidase and oxidase enzymes, followed by an increase in the toxic concentration of hydrogen peroxide. In general, Clotrimazole cream from Medipharm is prescribed to you according to the diagnosis and discretion of the doctor, but it is usually recommended for the following cases:
- Treatment of vaginal yeast infection (thrush) or vaginal candidiasis is one of the main reasons for the production of clotrimazole ointment and clotrimazole cream. Also, Kish Medipharm clotrimazole cream is specifically considered to be suitable for the treatment of vaginal yeast infection by having an applicator. Eliminating vaginal odor is another indirect function of this type of product, given that eliminating vaginal odor is due to eliminating the infection and not simply the effects of the drug itself.
- Athlete's foot, or tinea pedis, is a common and contagious disease. It is called athlete's foot because it is common among athletes. It is usually caused by wearing tight, poorly ventilated shoes or having a pre-existing wound. Also, because it is contagious, other gym members may also get the condition if they are in a place where this type of fungus is present.
- Cutaneous candidiasis is another condition for which clotrimazole cream is prescribed and recommended. Fungal infections can occur in areas of the body that are moist and creased, such as the armpits and groin. This medication is also intended to treat these types of infections.
Tips and how to use clotrimazole ointment or cream
Kish Medipharm topical clotrimazole cream is used as an antifungal medication to treat vaginal yeast infections. Clotrimazole ointment is also prescribed for vaginal odor. Given that fungal infections may spread to other parts of the body if hygiene is not observed or if used incorrectly, here are some important points you should know about using clotrimazole cream:
- Washing hands before and after applying clotrimazole cream is essential to prevent the spread of infection.
- Use intravaginally, once (at bedtime).
- Using the tube cap, pierce the aluminum cap and place the applicator over the opening of the tube. Then, fill the applicator with clotrimazole cream to a specified amount and, while lying on your back, insert it as far as possible into the vagina and empty it.
- The treatment period depends on the doctor's opinion, but typically 7 to 10 days are required for treatment.
- It should be noted that if you experience any symptoms such as excessive discharge, burning, itching, vaginal irritation, or severe abdominal pain, consult your doctor and discontinue use of the medication.
- In some rare cases, it has been reported that people may have a severe allergy to clotrimazole, in which case they should not use clotrimazole cream or ointment under any circumstances.
- Using the applicator for virgin women and girls younger than 12 years of age is also a contraindication to the use of this medication.
- Since clotrimazole cream is in pregnancy category B, it should be used under the supervision of a doctor and specialist during breastfeeding and pregnancy.
- This drug is produced by Kish Medipharm Pharmaceutical Company in a 20 and 50 gram tube in doses of 1 and 2 percent, along with an applicator inside the box.
- Clotrimazole cream should be stored below 30°C and protected from freezing.
Advantages of Clotrimazole Cream over Clotrimazole Ointment
Clotrimazole cream and clotrimazole ointment are two types of this medication that are used topically to treat fungal infections, but it should be kept in mind that using the medication in cream form includes benefits that we will discuss below.
The water base of clotrimazole cream allows it to be absorbed into the skin faster and does not leave a trace, so it is more suitable for parts of the body that are in contact with clothing more often. In addition, the water base of this drug does not clog the pores of the skin and does not cause acne and pimples. However, the clotrimazole ointment format does not provide this convenience and may cause acne and pimples on the skin due to its fat base. The ointment form is used for longer duration on the skin and long-term absorption in cases where there is a need for long-term use of the drug.
It should be noted that currently, which medication and dosage is right for you is completely determined by your doctor. Obviously, using 2% topical clotrimazole cream is stronger than 1% of the same product and provides a faster response to more severe infections. Before taking any medication, be sure to consult your doctor or pharmacist and read the brochures inside the boxes thoroughly.
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